Bocouture is a prescription only medicine indicated for the temporary improvement in the appearance of moderate to severe vertical lines between the eyebrows (glabellar frown lines), periorbital lines (crow’s feet lines) and horizontal forehead lines in adult patients under 65 years.
Mode of action:
Botulinum neurotoxin type A blocks cholinergic transmission at the neuromuscular junction by inhibiting the release of acetylcholine. The nerve terminals of the neuromuscular junction no longer respond to nerve impulses, and secretion of the neurotransmitter at the motor endplates is prevented. The action results in stopping the muscular contraction of the targeted muscles.
Contraindications of Bocouture:
-Hypersensitivity to the active substance or to any of the excipients.
-Generalised disorders of muscle activity (e.g. myasthenia gravis, Lambert- Eaton syndrome).
-Infection or inflammation at the proposed injection site.
Who should not use Bocouture?
-The injection of Bocouture is not recommended for patients with a history of aspiration or dysphagia.
-Patients suffering from amyotrophic lateral sclerosis
-Patients with other diseases which result in peripheral neuromuscular dysfunction
• In targeted muscles which display pronounced weakness or atrophy
Patient Information Leaflet: https://www.medicines.org.uk/emc/files/pil.600.pdf
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