Inject volume equal to filler injected. Direct into area of filler and necrosis. Massage and heat.
Repeat at 30min intervals, max 4 cycles. Re-assess signs (pain/capillary refill). Refer to A&E if not resolving.
No forearm dermal test patch needed.
Inject small volumes (0.1-0.2ml) in centre point of affected area. Use 30G needle or smaller (e.g. FMS)
Majority of effect seen within 12h. Repeat if necessary (min 48h, ideally 1-2 week intervals).
No forearm dermal test patch needed