BOTOX is widely known for its cosmetic benefits to enhance or improve deep lines for example eliminating deep facial skin wrinkles. BOTOX (200IU) is a prescription only medicine indicated for management of severe hyperhidrosis of the axillae, which does not respond to topical treatment with antiperspirants or antihidrotics and for temporary improvement in the appearance of moderate to severe vertical lines between the eyebrows (glabellar lines), moderate to severe lateral canthal lines (crow’s feet lines) and moderate to severe forehead lines in adult patients. There is limited phase 3 clinical data with BOTOX in patients older than 65 years.
Mode of action:
The active constituent in BOTOX (200IU) is a protein complex derived from Clostridium botulinum. The protein consists of type A neurotoxin and several other proteins. Intramuscular injection of the neurotoxin complex blocks cholinergic transport at the neuromuscular junction by preventing the release of acetylcholine. The action results in stopping the muscular contraction of the targeted muscles.
– Known hypersensitivity to botulinum toxin type A or to any of the excipients.
– Presence of infection at the proposed injection site(s).
Store in a refrigerator at 2–8°C
EMC for BOTOX 200IU: https://www.medicines.org.uk/emc/product/436/smpc
Patient Information Leaflet: https://www.medicines.org.uk/emc/files/pil.436.pdf
This is a prescription only medicine.
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